Policy action is more successful when it targets the population groups who need it the most. Error of inclusion (affecting beneficiaries who do not need it) and exclusion (leaving aside needy groups) are areas of particular concern when decision makers are confronted with alternative policies. Correct targeting also decreases the cost-effectiveness of the interventions, as does an adequate method of setting priorities at the local level. Identifying major challenges and opportunities for global food security would also shape needed policy and public intervention, hence targeting and priority setting are intertwined and subject to conjoined analyses. To this end, having a clear and reliable picture of the geographical distribution of marginalized populations and their specific needs is a prerequisite for a successful intervention. HarvestChoice strives to map targeted populations in sub-Saharan Africa and the farming dynamics they rely on using fine spatial resolution. Through careful data analysis, this information allows decision makers and researchers to adjust priorities across space and over time.